D. Thomas Rutkowski

Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

Kezhong Zhang, Xiaohua Shen, Jun Wu et al. · Cell · 2006 · 812 citations · Full text

Inflammation, Signal Transduction, Molecular Physiology +12

Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins

D. Thomas Rutkowski, Stacey Arnold, Corey N. Miller et al. · PLoS Biology · 2006 · 793 citations · Full text

Apoptosis, Cell Death, Pro-apoptotic Mrnas +16

ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress

Jun Wu, D. Thomas Rutkowski, Meghan Dubois et al. · Developmental Cell · 2007 · 678 citations · Full text

Chronic Stress, Signal Transduction, Cell Regulation +9

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

D. Thomas Rutkowski, Jun Wu, Sung-Hoon Back et al. · Developmental Cell · 2008 · 582 citations · Full text

Reductive Stress, Transcriptional Regulation, Hepatology +14

That which does not kill me makes me stronger: adapting to chronic ER stress

D. Thomas Rutkowski, Randal J. Kaufman · Trends in Biochemical Sciences · 2007 · 397 citations

Stress, Allostatic Load, Er Stress +6