Concepedia

NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian Cancer

Junping Li, Hong Hu, Hui Lian, Shuo Yang, Manting Liu, Jinping He, Bihui Cao, Dongni Chen, Yuling Hu, Yan Shen,

International Journal of Biological Sciences · 2024 · 30 citations · 57 references

DOIFull text

Open access

Concepts

Abstract

: These results indicate that CLDN6-CAR NK cells possess strong antitumor activity and represent a promising immunotherapeutic modality for ovarian cancer.

References

57

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

Enli Liu, David Marín, Pinaki P. Banerjee et al. · New England Journal of Medicine · 2020 · 2.1K citations · Full text

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Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Ángel García-Díaz, Daniel Sanghoon Shin, Blanca Homet Moreno et al. · Cell Reports · 2017 · 1.9K citations · Full text

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

Mathew L. Coleman, Erik Sahai, Margaret Yeo et al. · Nature Cell Biology · 2001 · 1.3K citations

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Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

Ye Li, David Hermanson, Branden S. Moriarity et al. · Cell stem cell · 2018 · 988 citations · Full text

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PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso et al. · The Journal of Experimental Medicine · 2017 · 877 citations · Full text

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