Robert T. Manguso

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Brian C. Miller, Debattama R. Sen, Rose Al Abosy et al. · Nature Immunology · 2019 · 2.1K citations · Full text

Life Sciences, Immunology, Oncology +14

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer et al. · Nature · 2017 · 1.1K citations

Medicine, Molecular Biology, Oncology +15

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso et al. · The Journal of Experimental Medicine · 2017 · 877 citations · Full text

Medicine, Immunology, Oncology +17

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot et al. · Nature · 2018 · 715 citations · Full text

Medicine, Cancer Biology, Oncology +14

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta‐Vellve et al. · Nature · 2021 · 362 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16