Margaret D. Zimmer

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Brian C. Miller, Debattama R. Sen, Rose Al Abosy et al. · Nature Immunology · 2019 · 1.9K citations · Full text

Mediate Tumor Control, Cancer Immunosurveillance, Immunology +8

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer et al. · Nature · 2017 · 1.1K citations · Full text

Identifies Ptpn2, Vivo Crispr, Immunology +8

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot et al. · Nature · 2018 · 688 citations · Full text

Cancer Immunosurveillance, Tumours Overcomes Resistance, Medicine +8

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta‐Vellve et al. · Nature · 2021 · 339 citations · Full text

Epigenetic Silencing, Cancer Immunosurveillance, Immunology +6

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker et al. · Nature Immunology · 2022 · 198 citations

Tumor Biology, Immunology, Tumor Immunity +10