Concepedia

Genetically Engineered Cells

Genetically Engineered Cells is a type of biological construct in which the genetic material of cells has been intentionally modified using recombinant DNA or genome editing technologies to introduce, remove, or alter specific traits for targeted biosensing functions within cell-based biosensor systems.

240

Publications

28.3K

Citations

1.7K

Authors

569

Institutions

Publications per year

2017–2026

79

Parents

Publications

240

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao et al. · Nature · 2020 · 10.1K citations · Full text

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The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 1.8K citations · Full text

, , +17

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

Sonam Dolma, Stephen L. Lessnick, William C. Hahn et al. · Cancer Cell · 2003 · 1.4K citations · Full text

, , +13

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

Ryosuke Kojima, Daniel Bojar, Giorgio Rizzi et al. · Nature Communications · 2018 · 736 citations · Full text

, , +15

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

Paul T. Golumbek, Audrey J. Lazenby, Hyam I. Levitsky et al. · Science · 1991 · 731 citations

, , +17

1–5 of 240

Authors

1.7K

  1. MC
    Michael C. Jensen

    University of Washington, United States

    4 publications · 923 citations

    4

    h-index

  2. MF
    Martin Fussenegger

    ETH Zurich, Switzerland

    4 publications · 878 citations

    4

    h-index

  3. NS
    Nancy S. Magnuson

    Washington State University, United States

    3 publications · 345 citations

    3

    h-index

  4. PD
    Philippe Duchâteau

    Cellectis (United States), United States

    3 publications · 187 citations

    3

    h-index

  5. DG
    Daniel G. MacArthur

    Broad Institute, United States

    4 publications · 22.3K citations

    3

    h-index

1–5 of 1.7K

Institutions

569

  1. Harvard University

    Cambridge, United States

    10 h-index

    62 publications

    162K citations

  2. University of Washington

    Seattle, United States

    9 h-index

    28 publications

    14.2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    32 publications

    4.8K citations

  4. Kyoto University

    Kyoto, Japan

    6 h-index

    21 publications

    823 citations

  5. ETH Zurich

    Zurich, Switzerland

    6 h-index

    23 publications

    4.4K citations

  6. University of Minnesota

    Minneapolis, United States

    6 h-index

    22 publications

    616 citations

  7. University of Toronto

    Toronto, Canada

    5 h-index

    11 publications

    243 citations

  8. Imperial College London

    London, United Kingdom

    5 h-index

    12 publications

    54.8K citations

1–8 of 569

Venues

  1. Human Gene Therapy

    12 publications · 475 citations

    11

    h-index

  2. Nature Communications

    9 publications · 1.4K citations

    9

    h-index

  3. PubMed

    Repository · 7 publications · 199 citations

    7

    h-index

  4. Molecular Therapy

    6 publications · 164 citations

    6

    h-index

  5. Blood

    5 publications · 877 citations

    5

    h-index

1–5