Concepedia

Supramolecular nanofiber of indomethacin derivative confers highly cyclooxygenase-2 (COX-2) selectivity and boosts anti-inflammatory efficacy

Deqing Lin, Xiaoning Xu, Lin Chen, Lei Chen, Mengyun Deng, Jinrun Chen, Zhibin Ren, Lei Lei, Jiaqing Wang, Jie Deng,

Journal of Controlled Release · 2023 · 20 citations · 29 references

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29

In situ click chemistry generation of cyclooxygenase-2 inhibitors

Atul Bhardwaj, Jatinder Kaur, Melinda Wuest et al. · Nature Communications · 2017 · 7.6K citations · Full text

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COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression

Naduviladath Vishvanath Chandrasekharan, Hu Dai, Katarina Roos et al. · Proceedings of the National Academy of Sciences · 2002 · 2K citations · Full text

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

Ravi G. Kurumbail, Anna M. Stevens, James K. Gierse et al. · Nature · 1996 · 1.9K citations

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A Single Amino Acid Difference between Cyclooxygenase-1 (COX-1) and −2 (COX-2) Reverses the Selectivity of COX-2 Specific Inhibitors

James K. Gierse, Joseph J. McDonald, Scott D. Hauser et al. · Journal of Biological Chemistry · 1996 · 411 citations · Full text

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Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors

Amit S. Kalgutkar, Alan B. Marnett, Brenda C. Crews et al. · Journal of Medicinal Chemistry · 2000 · 312 citations · Full text

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