Amit S. Kalgutkar

An oral SARS-CoV-2 M ^pro inhibitor clinical candidate for the treatment of COVID-19

Dafydd R. Owen, Charlotte Allerton, Annaliesa S. Anderson et al. · Science · 2021 · 1.8K citations · Full text

Viral Diagnostics, Worldwide Outbreak, Immunology +16

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

Tina R. White, Chad M. Renzelman, Arthur C Rand et al. · Nature Chemical Biology · 2011 · 373 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +7

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385

Scott W. Rowlinson, James R. Kiefer, Jeffery J. Prusakiewicz et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +16

Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors

Amit S. Kalgutkar, Alan B. Marnett, Brenda C. Crews et al. · Journal of Medicinal Chemistry · 2000 · 310 citations · Full text

Aspirin-like Molecules that Covalently Inactivate Cyclooxygenase-2

Amit S. Kalgutkar, Brenda C. Crews, Scott W. Rowlinson et al. · Science · 1998 · 260 citations