Allan R. Reyes

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice

Emily Cokorinos, Jake Delmore, Allan R. Reyes et al. · Cell Metabolism · 2017 · 259 citations · Full text

Metabolic Syndrome, Muscle Physiology, Muscle Function +15

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

Matthew F. Calabrese, Francis Rajamohan, Melissa S. Harris et al. · Structure · 2014 · 179 citations · Full text

Opposite Poles, Molecular Physiology, Signal Transduction +9

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore et al. · EBioMedicine · 2018 · 146 citations · Full text

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1<i>H</i>-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

Kimberly O. Cameron, Daniel W. Kung, Amit S. Kalgutkar et al. · Journal of Medicinal Chemistry · 2016 · 115 citations · Full text

Renal Inflammation, Pharmacotherapy, Insulin Signaling +19

Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy

Christopher T. Salatto, Russell Miller, Kimberly O. Cameron et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 79 citations · Full text