Daniel W. Kung

Highly Practical Methodology for the Synthesis of<scp>d</scp>- and<scp>l</scp>-α-Amino Acids,<i>N</i>-Protected α-Amino Acids, and<i>N</i>-Methyl-α-amino Acids

Andrew G. Myers, James L. Gleason, Tae‐young Yoon et al. · Journal of the American Chemical Society · 1997 · 181 citations

Combinatorial Chemistry, Engineering, Sarcosine Methyl Ester +18

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1<i>H</i>-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

Kimberly O. Cameron, Daniel W. Kung, Amit S. Kalgutkar et al. · Journal of Medicinal Chemistry · 2016 · 115 citations · Full text

Renal Inflammation, Pharmacotherapy, Insulin Signaling +19

Synthesis of highly epimerizable N-protected α-amino aldehydes of high enantiomeric excess

Andrew G. Myers, Boyu Zhong, Mohammad Movassaghi et al. · Tetrahedron Letters · 2000 · 99 citations

Engineering, Biochemistry, Organic Chemistry +7

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

David A. Griffith, Daniel W. Kung, William P. Esler et al. · Journal of Medicinal Chemistry · 2014 · 87 citations · Full text

Ketone Carbonyl, Pharmacotherapy, Metabolic Remodeling +17

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

Daniel P. Walker, Michael P. Zawistoski, Molly A. McGlynn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 86 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Signal Transduction +11