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Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

Daniel P. Walker, Michael P. Zawistoski, Molly A. McGlynn, Jiancheng Li, Daniel W. Kung, Peter C. Bonnette, Amy Baumann, Leonard Buckbinder, Janet A. Houser, Jason Boer,

Bioorganic & Medicinal Chemistry Letters · 2009 · 88 citations · 19 references

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19

Effect of Parathyroid Hormone (1-34) on Fractures and Bone Mineral Density in Postmenopausal Women with Osteoporosis

Robert M. Neer, Claude D. Arnaud, José Zanchetta et al. · New England Journal of Medicine · 2001 · 4.6K citations

, , +16

Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes

R. Scott Obach · Drug Metabolism and Disposition · 1999 · 1.2K citations

, , +17

Cellular Characterization of a Novel Focal Adhesion Kinase Inhibitor

Jill K. Slack‐Davis, Karen H. Martin, Robert W. Tilghman et al. · Journal of Biological Chemistry · 2007 · 483 citations · Full text

, , +17

Sulfoximines: Structures, Properties and Synthetic Applications

Michael Reggelin, C. ZUR · Synthesis · 2000 · 401 citations

, , +7

Sulfoximines: Synthesis and Catalytic Applications

Hiroaki Okamura, Carsten Bolm · Chemistry Letters · 2004 · 279 citations

, , +7