Concepedia

Targeting ONECUT3 blocks glycolytic metabolism and potentiates anti-PD-1 therapy in pancreatic cancer

Pengcheng Chen, Yong Ning, Hui Li, Jin-Gen Su, Jiang-Bo Shen, Qingchun Feng, Shu‐Heng Jiang, Pei-Dong Shi, Runsheng Guo

Cellular Oncology · 2023 · 20 citations · 27 references

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27

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

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Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih‐Hao Chang, Jing Qiu, David O’Sullivan et al. · Cell · 2015 · 3.2K citations · Full text

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Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo et al. · Nature · 2014 · 2.9K citations

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Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

Stefani Spranger, Riyue Bao, Thomas F. Gajewski · Nature · 2015 · 2.8K citations

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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.2K citations · Full text

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