Lipofuscin Granule Accumulation Requires Autophagy Activation

The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes

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Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation

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Cell Autophagy, Autophagy, Lipophagy +4

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

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Metabolic Syndrome, Oncology, Healthy Ageing +8

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

Jinghui Zhao, Bo Zhai, Steven P. Gygi et al. · Proceedings of the National Academy of Sciences · 2015 · 472 citations · Full text

Mitophagy, Proteasome, Cell Autophagy +17

SIRT1 is downregulated by autophagy in senescence and ageing

Caiyue Xu, Lu Wang, Parinaz Fozouni et al. · Nature Cell Biology · 2020 · 452 citations · Full text

Cell Autophagy, Mitophagy, Longevity +6