Chinese chestnut shell polyphenol extract regulates the JAK2/STAT3 pathway to alleviate high-fat diet-induced, leptin-resistant obesity in mice

Suwen Liu, Wenhong Jiang, Chang Liu, Shuo Guo, Hao Wang, Xuedong Chang

Food & Function · 2023 · 18 citations · 40 references

Concepts

Abstract

Chinese chestnut shell polyphenol (CSP) reduce inflammation and increase antioxidant capacity, and activating the LEPR-JAK2/STAT3-PTP1B-SOCS-3 signal transduction pathway to alleviate high-fat diet–induced, leptin-resistant obesity in mice.

References

40