Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Positional cloning of the mouse obese gene and its human homologue

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Life Sciences, Genetics, Molecular Genetics +12

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

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Life Sciences, Neurobiology, Neuroscience +17

mouse brain in stereotaxic coordinates

Keith B.J. Franklin, George Paxinos · 1997 · 3.1K citations

Medicine, Neurobiology, Neuroscience +9

Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

I. Sadaf Farooqi, Susan A. Jebb, Gill Langmack et al. · New England Journal of Medicine · 1999 · 2K citations · Full text

Medicine, Endocrinology, Pediatrics +17

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

Jeffrey L. Halaas, Carol N. Boozer, J. R. Blair‐West et al. · Proceedings of the National Academy of Sciences · 1997 · 1K citations

Medicine, Endocrinology, Physiology +17