Concepedia

Leptin Signaling

Leptin Signaling is a hormonal signaling pathway that regulates metabolic homeostasis by transmitting satiety signals from adipose tissue to the hypothalamus, thereby modulating energy balance and appetite in response to circulating levels of the adipokine leptin.

5.5K

Publications

477.4K

Citations

23.6K

Authors

3.6K

Institutions

Publications per year

2017–2026

877

Parents

Publications

5.5K

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Margherita Maffei, Jeffrey L. Halaas, Éric Ravussin et al. · Nature Medicine · 1995 · 3.7K citations

, , +15

Identification and expression cloning of a leptin receptor, OB-R

Louis A. Tartaglia, Marlene Dembski, Xun Weng et al. · Cell · 1995 · 3.5K citations · Full text

, , +10

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Kenneth R. Watterson, Dawn Bestow, Jennifer Gallagher et al. · Neurosignals · 2012 · 3.4K citations · Full text

, , +17

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

L. Arthur Campfield, Françoise J. Smith, Yves Guisez et al. · Science · 1995 · 3.3K citations

, , +17

Role of leptin in the neuroendocrine response to fasting

Rexford S. Ahima, Daniel Prabakaran, Christos S. Mantzoros et al. · Nature · 1996 · 3.1K citations

, , +11

1–5 of 5.5K

Authors

23.6K

  1. MG
    Martin G. Myers

    University of Michigan, United States

    75 publications · 10.9K citations

    48

    h-index

  2. JK
    Joel K. Elmquist

    The University of Texas Southwestern Medical Center, United States

    44 publications · 13.2K citations

    37

    h-index

  3. JS
    Jeffrey S. Flier

    Harvard University, United States

    36 publications · 17.7K citations

    34

    h-index

  4. SC
    Streamson C. Chua

    Albert Einstein College of Medicine, United States

    38 publications · 8.7K citations

    34

    h-index

  5. JM
    Jeffrey M. Friedman

    Rockefeller University, United States

    35 publications · 16.6K citations

    31

    h-index

1–5 of 23.6K

Institutions

3.6K

  1. Harvard University

    Cambridge, United States

    89 h-index

    678 publications

    179.1K citations

  2. Beth Israel Deaconess Medical Center

    Boston, United States

    80 h-index

    504 publications

    144.5K citations

  3. University of Washington

    Seattle, United States

    64 h-index

    321 publications

    76.3K citations

  4. The University of Texas Southwestern Medical Center

    Dallas, United States

    63 h-index

    480 publications

    91K citations

  5. University of Michigan

    Ann Arbor, United States

    62 h-index

    504 publications

    57.9K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    62 h-index

    199 publications

    104.4K citations

  7. Inserm

    Paris, France

    55 h-index

    603 publications

    72.1K citations

  8. National Institutes of Health

    Bethesda, United States

    48 h-index

    280 publications

    55.1K citations

1–8 of 3.6K

Venues

  1. Endocrinology

    321 publications · 30.3K citations

    99

    h-index

  2. Diabetes

    156 publications · 21.8K citations

    84

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 76 publications · 17.8K citations

    62

    h-index

  4. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 126 publications · 11.5K citations

    62

    h-index

  5. International Journal of Obesity

    145 publications · 9.3K citations

    59

    h-index

1–5