Jeffrey M. Friedman

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.5K citations

Medicine, Endocrinology, Nutritional Sciences +17

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Margherita Maffei, Jeffrey L. Halaas, Éric Ravussin et al. · Nature Medicine · 1995 · 3.7K citations

Medicine, Endocrinology, Physiology +15

Abnormal splicing of the leptin receptor in diabetic mice

Gwo‐Hwa Lee, R Proenca, Jason Montez et al. · Nature · 1996 · 2.4K citations

Life Sciences, Endocrinology, Molecular Biology +13

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

Michael A. Cowley, Roy G. Smith, Sabrina Diano et al. · Neuron · 2003 · 1.7K citations · Full text

Life Sciences, Endocrinology, Neuroscience +10