Concepedia

Publication | Open Access

Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs

DOIFull Paper Access

23

Citations

72

References

2022

Year

André A. Teixeira, Sara D’Angelo, M. Frank Erasmus, Camila Leal‐Lopes, Fortunato Ferrara, Laura Spector, Leslie Naranjo, Esteban Molina, Tamara Max, Ashley DeAguero,
mAbs

Abstract

CDR: complementarity determining region; FACS: fluorescence-activated cell sorting; k<sub>a</sub>: association rate; k<sub>d</sub>: dissociation rate; K<sub>D</sub>: dissociation constant; scFv: single-chain variable fragment; SPR: surface plasmon resonance.

References

YearCitations

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