Antibody Specificity Engineering is the academic discipline within antibody engineering that focuses on the rational design and alteration of antigen-binding regions to achieve selective recognition of specific molecular targets.
1.7K
Publications
111.6K
Citations
9.7K
Authors
1.8K
Institutions
Publications per year
2017–2026
494
Parents
Children
Antibody Affinity Trade-offsAntibody Escape Variant MappingAntibody Loop EngineeringAntibody Specificity Trade-offsAntigen Specificity ProfilingAntigen-binding Site DesignBinding Specificity OptimizationBispecific Antibody Specificity DesignChain Pairing OptimizationDisplay Technology Screening
Publications
1.7K
Continuous cultures of fused cells secreting antibody of predefined specificity
Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations
Pharmacy, Cell Biology, Immunology +11
Drug assay using antibody mimics made by molecular imprinting
George Vlatakis, L. Andersson, Ralf R. Müller et al. · Nature · 1993 · 1.7K citations
Broad neutralization coverage of HIV by multiple highly potent antibodies
Laura M. Walker, Michael Huber, Katie J. Doores et al. · Nature · 2011 · 1.5K citations
Replacing the complementarity-determining regions in a human antibody with those from a mouse
Peter Jones, Paul H. Dear, Jefferson Foote et al. · Nature · 1986 · 1.4K citations
1–5 of 1.7K
Authors
9.7K
- DR
20
h-index
- CF
17
h-index
- RA
14
h-index
- JDJames D. Marks
University of California, San Francisco, United States
14 publications · 1.6K citations
14
h-index
- IA
12
h-index
1–5 of 9.7K
Institutions
1.8K
Scripps Research Institute
San Diego, United States
41 h-index
368 publications
56.5K citations
Centre National de la Recherche Scientifique
Paris, France
25 h-index
161 publications
6K citations
National Institutes of Health
Bethesda, United States
25 h-index
215 publications
12.3K citations
National Cancer Institute
Bethesda, United States
22 h-index
81 publications
4.4K citations
Massachusetts Institute of Technology
Cambridge, United States
18 h-index
87 publications
6K citations
University of California, San Francisco
San Francisco, United States
18 h-index
115 publications
9.3K citations
Harvard University
Cambridge, United States
18 h-index
63 publications
3.9K citations
University of Oxford
Oxford, United Kingdom
17 h-index
56 publications
3.3K citations
1–8 of 1.8K
Venues
- Proceedings of the National Academy of Sciences
PNAS · 53 publications · 7.9K citations
40
h-index
- Journal of Molecular Biology
JMB · 46 publications · 4.9K citations
34
h-index
- mAbs
45 publications · 2K citations
30
h-index
- Journal of Immunological Methods
62 publications · 2.1K citations
29
h-index
- Journal of Biological Chemistry
JBC · 45 publications · 2.4K citations
28
h-index
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