Concepedia

TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation

Linhan Wang, Jiqiang Li, Qingchen Wang, Man-Xi Ge, Jia Ji, Di Liu, Zhiyuan Wang, Yang Cao, Yaoyang Zhang, Zai-Rong Zhang

Molecular Cell · 2022 · 28 citations · 31 references

DOI

Concepts

References

31

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.4K citations · Full text

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Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

Xiaotian Zhu, Xun Zhao, William F. Burkholder et al. · Science · 1996 · 1.3K citations

Molecular code for transmembrane-helix recognition by the Sec61 translocon

Tara Hessa, Nadja M. Meindl‐Beinker, Andreas Bernsel et al. · Nature · 2007 · 727 citations · Full text

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Defining human ERAD networks through an integrative mapping strategy

John C. Christianson, James A. Olzmann, Thomas A. Shaler et al. · Nature Cell Biology · 2011 · 504 citations · Full text

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A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri et al. · Nature Medicine · 2018 · 414 citations

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