Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

Xiaotian Zhu, Xun Zhao, William F. Burkholder, +4

Science

Structure of nucleotide‐binding domain 1 of the cystic fibrosis transmembrane conductance regulator

H.A. Lewis, Sean G. Buchanan, S.K. Burley, +21

The EMBO Journal

Structural characterization of the human respiratory syncytial virus fusion protein core

Xun Zhao, Mona Singh, V.N. Malashkevich, +1

Proceedings of the National Academy of Sciences

Structural CharacterizationViral ReplicationViral Polymerase StructureImmunologyMolecular Biology +14

Impact of the ΔF508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure

H.A. Lewis, Xun Zhao, Chi Chiu Wang, +11

Journal of Biological Chemistry

Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ

Won-Chul Suh, William F. Burkholder, Chi Zen Lu, +3

Proceedings of the National Academy of Sciences

Structural BioinformaticsProtein AssemblyBiomolecular Structure PredictionDna AnalysisMolecular Biology +14

Specificity of DnaK-peptide Binding

Alexander Gragerov, Li Zeng, Xun Zhao, +2

Journal of Molecular Biology

Protein ChemistrySignal TransductionBound PeptidesProtein AssemblyBiochemistry +12

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD⁺) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Xun Zhao, Dagart Allison, Bradley Condon, +9

Journal of Medicinal Chemistry

Crystal StructureAldo-keto ReductaseMolecular RegulationMolecular BiologyEpigenetics +18

Structure of the Bcr-Abl oncoprotein oligomerization domain.

Xun Zhao, Saghi Ghaffari, Harvey Lodish, +2

PubMed

Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide‐binding domain 1

Irina I. Protasevich, Zhengrong Yang, Chi Wang, +6

Protein Science

EngineeringProtein AssemblyMolecular BiologyAnalytical UltracentrifugationMolecular Research +15

Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis

Chi Wang, Irina I. Protasevich, Zhengrong Yang, +8

Protein Science