Microbiology Spectrum · 2022 · 28 citations · 45 references
Life SciencesBiotechnologyMolecular BiologyGenome EditingGenomicsSynthetic BiologyBacteriophage GeneticsCrispr-based EngineeringCrispr-cas SystemsPhage GeneticsBacteriophagesCrispr-based Genome EngineeringCrispr-cas ArraysCrispr-cas Genome EditingGene DeletionGenome Editing In MicrobesPhage Functional GenomicsPhage Genome Engineering
Bacteriophages are the most numerous organisms on earth and are known for their diverse lifestyles. Since the discovery of bacteriophages, our knowledge of the wider biological world has undergone immense and unforeseen changes.
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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.3K citations
Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
Stan J. J. Brouns, Matthijs M. Jore, Magnus Lundgren et al. · Science · 2008 · 2.6K citations · Full text
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Elitza Deltcheva, Krzysztof Chylinski, Cynthia M. Sharma et al. · Nature · 2011 · 2.6K citations · Full text
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang, David Bikard, David Cox et al. · Nature Biotechnology · 2013 · 2.5K citations
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
Omar O. Abudayyeh, Jonathan S. Gootenberg, Silvana Konermann et al. · Science · 2016 · 2.4K citations · Full text