Concepedia

Ring replacement recommender: Ring modifications for improving biological activity

Peter Ertl, Eva Altmann, Sophie Racine, Richard A. Lewis

European Journal of Medicinal Chemistry · 2022 · 36 citations · 20 references

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References

20

ChEMBL: towards direct deposition of bioassay data

David Méndez, Anna Gaulton, A. Patrícia Bento et al. · Nucleic Acids Research · 2018 · 2.4K citations · Full text

, , +13

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

Rainer Wilcken, Markus O. Zimmermann, Andreas Lange et al. · Journal of Medicinal Chemistry · 2012 · 1.3K citations · Full text

, , +15

A systematic analysis of atomic protein–ligand interactions in the PDB

Renato Ferreira de Freitas, Matthieu Schapira · MedChemComm · 2017 · 593 citations · Full text

, , +16

Functional group contributions to drug-receptor interactions

Peter R. Andrews, David J. Craik, Jennifer L. Martin · Journal of Medicinal Chemistry · 1984 · 533 citations

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Utilization of operational schemes for analog synthesis in drug design

John G. Topliss · Journal of Medicinal Chemistry · 1972 · 459 citations

, , +5