Concepedia

Ring Atom Replacement

Ring Atom Replacement is a chemical modification strategy within atom replacement methods that specifically involves substituting an atom in a cyclic molecular structure with a different atom or functional group to alter the ring's electronic, steric, or pharmacological properties while maintaining its cyclic topology.

14

Publications

490

Citations

73

Authors

26

Institutions

Publications per year

2017–2026

5

Parents

Publications

14

Isofagomine, a Potent, New Glycosidase Inhibitor

Tina M. Jespersen, Wenling Dong, Michael R. Sierks et al. · Angewandte Chemie International Edition in English · 1994 · 172 citations

, , +17

Bioorthogonal Activation of Deep Red Photoredox Catalysis Inducing Pyroptosis

Jungryun Kim, Yunjie Xu, Jong Hyeon Lim et al. · Journal of the American Chemical Society · 2024 · 51 citations · Full text

, , +15

Bridging the pyridine-pyridazine synthesis gap by skeletal editing

Mikus Puriņš, Hikaru Nakahara, Mark D. Levin · Science · 2025 · 49 citations · Full text

, , +15

Recent advances in carbon atom addition for ring-expanding single-atom skeletal editing

Ting Yuan · Organic Chemistry Frontiers · 2024 · 37 citations

, , +13

Ring replacement recommender: Ring modifications for improving biological activity

Peter Ertl, Eva Altmann, Sophie Racine et al. · European Journal of Medicinal Chemistry · 2022 · 36 citations · Full text

, , +16

1–5 of 14

Authors

73

  1. XZ
    Xinhui Zhang

    Zhengzhou University, China

    1 publications · 12 citations

    1

    h-index

  2. MM
    Mahmood M. Barbooti

    University of Technology - Iraq, Iraq

    1 publications · 11 citations

    1

    h-index

  3. SD
    S. Deepa

    Pondicherry University, India

    1 publications · 32 citations

    1

    h-index

  4. BZ
    Bing Zhao

    Zhengzhou University, China

    1 publications · 12 citations

    1

    h-index

  5. EA
    Eva Altmann

    Novartis (Switzerland), Switzerland

    1 publications · 36 citations

    1

    h-index

1–5 of 73

Institutions

26

  1. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    6 publications

    146 citations

  2. Korea University

    Seoul, South Korea

    1 h-index

    6 publications

    306 citations

  3. MRC Centre for Regenerative Medicine

    Edinburgh, United Kingdom

    1 h-index

    2 publications

    102 citations

  4. Harbin Institute of Technology

    Harbin, China

    1 h-index

    2 publications

    74 citations

  5. Sungkyunkwan University

    Seoul, South Korea

    1 h-index

    3 publications

    153 citations

  6. Shenzhen University

    Shenzhen, China

    1 h-index

    2 publications

    102 citations

  7. Pondicherry University

    Puducherry, India

    1 h-index

    4 publications

    128 citations

  8. University College London

    London, United Kingdom

    1 h-index

    1 publications

    24 citations

1–8 of 26

Venues

  1. European Journal of Medicinal Chemistry

    2 publications · 48 citations

    2

    h-index

  2. 2

    h-index

  3. Journal of the American Chemical Society

    JACS · 2 publications · 66 citations

    2

    h-index

  4. Journal of Medicinal Chemistry

    1 publications · 24 citations

    1

    h-index

  5. ACS Medicinal Chemistry Letters

    1 publications · 25 citations

    1

    h-index

1–5