Concepedia

Intracellular proteolysis

Marc W. Kirschner

Trends in Cell Biology · 1999 · 58 citations · 27 references

DOI

References

27

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Martin Scheffner, Bruce A. Werness, Jon M. Huibregtse et al. · Cell · 1990 · 4K citations

, , +14

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

, , +14

Cyclin is degraded by the ubiquitin pathway

Michael Glotzer, Andrew W. Murray, Marc W. Kirschner · Nature · 1991 · 2.4K citations

, , +6

Hsp90 as a capacitor for morphological evolution

Suzanne L. Rutherford, Susan Lindquist · Nature · 1998 · 2.3K citations

, , +5

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg et al. · Cell · 1994 · 2.1K citations

, , +11