Vito J. Palombella

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg et al. · Cell · 1994 · 2.1K citations

Transcriptional Regulation, Protein Function, Signal Transduction +14

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

Teru Hideshima, Paul G. Richardson, D Chauhan et al. · PubMed · 2001 · 1.5K citations

Proteasome Inhibitors, Human Mm Cells, Apoptosis +19

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

Proteasome Inhibitors, Effective Antitumor Agents, Proteasome +21

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

Zhe Chen, Jeremiah Hagler, Vito J. Palombella et al. · Genes & Development · 1995 · 1.3K citations · Full text

Signal Transduction Pathways, Molecular Regulation, Proteasome +16

PI3Kγ is a molecular switch that controls immune suppression

Megan M. Kaneda, Karen Messer, Natacha Ralainirina et al. · Nature · 2016 · 1.1K citations · Full text

Molecular Immunology, Immune Regulation, Immunology +6