Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

Donna D. Zhang, Mark Hannink · Molecular and Cellular Biology · 2003 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Identification of Lignans as Major Components in the Phenolic Fraction of Olive Oil

Robert W. Owen, Walter Mier, Attilio Giacosa et al. · Clinical Chemistry · 2000 · 273 citations

Agriculture, Biochemistry, Food Science +13

Neuroprotective Effects of the Citrus Flavanones against H₂O₂-Induced Cytotoxicity in PC12 Cells

Sam-Long Hwang, Gow‐Chin Yen · Journal of Agricultural and Food Chemistry · 2008 · 194 citations

Life Sciences, Neuroscience, Pharmacology +17

Neuroprotective effect of crocin against rotenone-induced Parkinson's disease in rats: Interplay between PI3K/Akt/mTOR signaling pathway and enhanced expression of miRNA-7 and miRNA-221

Rania M. Salama, Ghada A. Abdel‐Latif, Samah S. Abbas et al. · Neuropharmacology · 2019 · 158 citations

Medicine, Neuroscience, Pharmacology +15

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis

Yunjie Wang, Xin‐Yuan Guan, Chenglong Gao et al. · Pharmacological Research · 2021 · 113 citations

Medicine, Cell Biology, Pharmacology +17