Concepedia

Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells

Kareem A. Heslop, Pieter B. Burger, Christiana S. Kappler, Ashish K. Solanki, Mónika Göőz, Yuri K. Peterson, Catherine M. Mills, Thomas Z. Benton, Stephen A. Duncan, Patrick M. Woster,

Biomedicine & Pharmacotherapy · 2022 · 15 citations · 37 references

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References

37

THE METABOLISM OF TUMORS IN THE BODY

Otto Warbürg, Franz Wind, Erwin Negelein · The Journal of General Physiology · 1927 · 4.3K citations · Full text

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

Christopher Baines, Robert A. Kaiser, Tatiana Sheiko et al. · Nature Cell Biology · 2007 · 962 citations · Full text

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We need to talk about the Warburg effect

Ralph J. DeBerardinis, Navdeep S. Chandel · Nature Metabolism · 2020 · 820 citations

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An uncoupling channel within the c-subunit ring of the F <sub>1</sub> F <sub>O</sub> ATP synthase is the mitochondrial permeability transition pore

Kambiz N. Alavian, Gisela Beutner, Emma Lazrove et al. · Proceedings of the National Academy of Sciences · 2014 · 568 citations · Full text

The crystal structure of mouse VDAC1 at 2.3 Å resolution reveals mechanistic insights into metabolite gating

Rachna Ujwal, Duilio Cascio, Jacques‐Philippe Colletier et al. · Proceedings of the National Academy of Sciences · 2008 · 529 citations · Full text

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