Patrick M. Woster

The natural polyamine spermine functions directly as a free radical scavenger

Hyo Chol Ha, Nilantha Sirisoma, Periannan Kuppusamy et al. · Proceedings of the National Academy of Sciences · 1998 · 679 citations

Life Sciences, Biochemistry, Cell Biology +12

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Tino Schenk, Weihsu Claire Chen, Stefanie Göllner et al. · Nature Medicine · 2012 · 654 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Polyamine catabolism contributes to enterotoxigenic <i>Bacteroides fragilis</i> -induced colon tumorigenesis

Andrew C. Goodwin, Christina E. DeStefano Shields, Shaoguang Wu et al. · Proceedings of the National Academy of Sciences · 2011 · 597 citations

Medicine, Oncology, Pathobiology +17

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

James E. Rider, Amy Hacker, C. A. Mackintosh et al. · Amino Acids · 2007 · 315 citations

Life Sciences, Biochemistry, Toxicology +15

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

Paul F. Hollenberg, David Edwards, Kan He et al. · UNC Libraries · 2019 · 311 citations · Full text

Agriculture, Pharmacokinetics, Pharmacology +9