Concepedia

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Tino Schenk, Weihsu Claire Chen, Stefanie Göllner, Louise Howell, Liqing Jin, Katja Hebestreit, Hans‐Ulrich Klein, Andreea C. Popescu, Alan Burnett, Ken Mills,

Nature Medicine · 2012 · 654 citations · 30 references

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30

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

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Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

Yujiang Geno Shi, Yujiang Geno Shi, Fei Lan et al. · Cell · 2004 · 4K citations · Full text

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber, Junwei Shi, Eric Wang et al. · Nature · 2011 · 1.9K citations

, , +9

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

B Bernstein, Michael Kamal, Kerstin Lindblad‐Toh et al. · Cell · 2005 · 1.5K citations · Full text

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The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

Jing Wang, Sarah Hevi, Julia K. Kurash et al. · Nature Genetics · 2008 · 813 citations

, , +11