Louise Howell

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Tino Schenk, Weihsu Claire Chen, Stefanie Göllner et al. · Nature Medicine · 2012 · 654 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes

Matthew Clarke, Alan Mackay, Britta Ismer et al. · Cancer Discovery · 2020 · 278 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

Rebecca M. Hill, Sanne Kuijper, Janet C. Lindsey et al. · Cancer Cell · 2014 · 213 citations · Full text

Medicine, Genetics, Oncology +17

The Histone Deacetylase 9 Gene Encodes Multiple Protein Isoforms

Kevin Petrie, Fabien Guidez, Louise Howell et al. · Journal of Biological Chemistry · 2003 · 142 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

<i>De novo</i> phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

Gabriela Andrejeva, Sharon Gowan, Gigin Lin et al. · Autophagy · 2019 · 109 citations · Full text

Life Sciences, Cell Biology, Oncology +17