Alan Mackay

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak et al. · Cell · 2016 · 1K citations · Full text

Medicine, Neurosurgery, Oncology +14

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay et al. · Cell stem cell · 2010 · 808 citations · Full text

Medicine, Cancer Biology, Oncology +16

<i>FGFR1</i> Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

Nicholas C. Turner, Alex Pearson, Rachel Sharpe et al. · Cancer Research · 2010 · 738 citations · Full text

Medicine, Cancer Biology, Oncology +17

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

David Castel, Cathy Philippe, Raphaël Calmon et al. · Acta Neuropathologica · 2015 · 668 citations · Full text

Medicine, Genetics, Oncology +17

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Pawel Buczkowicz, Christine M. Hoeman, Patricia Rakopoulos et al. · Nature Genetics · 2014 · 654 citations · Full text

Medicine, Genetics, Oncology +13