Alan Mackay

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak et al. · Cell · 2016 · 973 citations · Full text

Neuro-oncology, Molecular Classification, Cerebral Organoid +8

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay et al. · Cell stem cell · 2010 · 800 citations · Full text

Lineage Plasticity, Breast Oncology, Developmental Biology +8

<i>FGFR1</i> Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

Nicholas C. Turner, Alex Pearson, Rachel Sharpe et al. · Cancer Research · 2010 · 712 citations · Full text

Endocrine Oncology, Breast Oncology, Endocrine-related Cancer +14

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Pawel Buczkowicz, Christine M. Hoeman, Patricia Rakopoulos et al. · Nature Genetics · 2014 · 643 citations · Full text

Neuro-oncology, Radiation Oncology, Engineering +10

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

David Castel, Cathy Philippe, Raphaël Calmon et al. · Acta Neuropathologica · 2015 · 642 citations · Full text

Hist1h3b K27m Mutations, Pathology, High-grade Gliomas +17