David Castel

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

Marie‐Agnès Dillies, Andréa Rau, Julie Aubert et al. · Briefings in Bioinformatics · 2012 · 1.4K citations · Full text

Life Sciences, Biostatistics, Molecular Biology +14

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender, Yujie Tang, Anders M. Lindroth et al. · Cancer Cell · 2013 · 842 citations · Full text

Medicine, Genetics, Molecular Biology +13

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

David Castel, Cathy Philippe, Raphaël Calmon et al. · Acta Neuropathologica · 2015 · 668 citations · Full text

Medicine, Genetics, Oncology +17

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Kathryn R. Taylor, Alan Mackay, Nathalène Truffaux et al. · Nature Genetics · 2014 · 525 citations · Full text

Medicine, Molecular Genetics, Oncology +10

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

Philippos Mourikis, Ramkumar Sambasivan, David Castel et al. · Stem Cells · 2011 · 512 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17