Nathalène Truffaux

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender, Yujie Tang, Anders M. Lindroth et al. · Cancer Cell · 2013 · 821 citations · Full text

Neuro-oncology, Radiation Oncology, Pediatric Brain Tumors +9

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Catherine S. Grasso, Yujie Tang, Nathalène Truffaux et al. · Nature Medicine · 2015 · 686 citations · Full text

Neuro-oncology, Therapeutic Targets, Tumor Targeting +6

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

David Castel, Cathy Philippe, Raphaël Calmon et al. · Acta Neuropathologica · 2015 · 642 citations · Full text

Hist1h3b K27m Mutations, Pathology, High-grade Gliomas +17

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Kathryn R. Taylor, Alan Mackay, Nathalène Truffaux et al. · Nature Genetics · 2014 · 514 citations · Full text

Neuro-oncology, Somatic Variant, Tumor Heterogeneity +6

A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium

Sabine Mueller, Payal Jain, Winnie S. Liang et al. · International Journal of Cancer · 2019 · 127 citations