Brent A. Orr

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak et al. · Cell · 2016 · 1K citations · Full text

Medicine, Neurosurgery, Oncology +14

cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading

David N. Louis, Pieter Wesseling, Kenneth Aldape et al. · Brain Pathology · 2020 · 534 citations · Full text

Medicine, Oncology, Pathology +13

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog–Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032

Giles Robinson, Brent A. Orr, Gang Wu et al. · Journal of Clinical Oncology · 2015 · 460 citations · Full text

Medicine, Oncology, Pharmacology +15

Resolving medulloblastoma cellular architecture by single-cell genomics

Volker Hovestadt, Kyle Smith, Laure Bihannic et al. · Nature · 2019 · 430 citations · Full text

Life Sciences, Cancer Biology, Oncology +14

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Charles Y. Lin, Serap Erkek, Yiai Tong et al. · Nature · 2016 · 399 citations · Full text

Medicine, Genetics, Molecular Genetics +14