Matthew Clarke

Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

Joaquı́n Mateo, Núria Porta, Diletta Bianchini et al. · The Lancet Oncology · 2019 · 632 citations · Full text

Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition

Jane Goodall, Joaquı́n Mateo, Wei Yuan et al. · Cancer Discovery · 2017 · 410 citations · Full text

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Michal Zimmermann, Olga Murina, Martin A.M. Reijns et al. · Nature · 2018 · 402 citations · Full text

Natural Sciences, Genetics, Parp-trapping Lesions +10

Genomics of lethal prostate cancer at diagnosis and castration resistance

Joaquı́n Mateo, George Seed, Cláudia Bertan et al. · Journal of Clinical Investigation · 2019 · 292 citations · Full text

Urology, Oncology, Genomic Aberrations +13

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes

Matthew Clarke, Alan Mackay, Britta Ismer et al. · Cancer Discovery · 2020 · 264 citations · Full text