George Seed

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

Joaquı́n Mateo, Suzanne Carreira, Shahneen Sandhu et al. · New England Journal of Medicine · 2015 · 2.2K citations · Full text

Medicine, Molecular Biology, Oncology +17

Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

Joaquı́n Mateo, Núria Porta, Diletta Bianchini et al. · The Lancet Oncology · 2019 · 644 citations · Full text

Medicine, Oncology, Pharmacotherapy +17

Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer

Alec Paschalis, Beshara Sheehan, Ruth Riisnaes et al. · European Urology · 2019 · 465 citations · Full text

Medicine, Oncology, Urology +17

Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition

Jane Goodall, Joaquı́n Mateo, Wei Yuan et al. · Cancer Discovery · 2017 · 422 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

Adam Sharp, Ilsa M. Coleman, Wei Yuan et al. · Journal of Clinical Investigation · 2018 · 393 citations · Full text

Medicine, Endocrinology, Oncology +17