Paul F. Hollenberg

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

Kan He, K. R. Krishna Iyer, Roger N. Hayes et al. · Chemical Research in Toxicology · 1998 · 312 citations

Medicine, Biochemistry, Pharmacology +17

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

Paul F. Hollenberg, David Edwards, Kan He et al. · UNC Libraries · 2019 · 311 citations · Full text

Agriculture, Pharmacokinetics, Pharmacology +9

SILYBIN INACTIVATES CYTOCHROMES P450 3A4 AND 2C9 AND INHIBITS MAJOR HEPATIC GLUCURONOSYLTRANSFERASES

Chitra Sridar, Theunis C. Goosen, Ute M. Kent et al. · Drug Metabolism and Disposition · 2004 · 192 citations

Medicine, Biochemistry, Pharmacology +17

Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands

Krishna C. Chimalakonda, Kathryn A. Seely, Stacie M. Bratton et al. · Drug Metabolism and Disposition · 2012 · 186 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Cytochrome P450-Catalyzed Hydroxylation of Mechanistic Probes that Distinguish between Radicals and Cations. Evidence for Cationic but Not for Radical Intermediates

Martin Newcomb, Runnan Shen, Seung-Yong Choi et al. · Journal of the American Chemical Society · 2000 · 177 citations

Medicine, Biochemistry, Pharmacology +17