Theunis C. Goosen

In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies

Lifei Wang, Donglu Zhang, Nirmala Raghavan et al. · Drug Metabolism and Disposition · 2009 · 251 citations

SILYBIN INACTIVATES CYTOCHROMES P450 3A4 AND 2C9 AND INHIBITS MAJOR HEPATIC GLUCURONOSYLTRANSFERASES

Chitra Sridar, Theunis C. Goosen, Ute M. Kent et al. · Drug Metabolism and Disposition · 2004 · 192 citations

Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors

Robert L. Walsky, Jonathan Bauman, Karine Bourcier et al. · Drug Metabolism and Disposition · 2012 · 149 citations

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Manthena V. S. Varma, Yurong Lai, Bo Feng et al. · Pharmaceutical Research · 2012 · 128 citations

Pharmacokinetic Modeling, Hepatology, Medicine +8

Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity

Abdul Mutlib, Theunis C. Goosen, Jonathan Bauman et al. · Chemical Research in Toxicology · 2006 · 123 citations

Aldo-keto Reductase, Glycobiology, Udp-glucuronosyltransferases 1A1 +22