Jonathan Bauman

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

Tina R. White, Chad M. Renzelman, Arthur C Rand et al. · Nature Chemical Biology · 2011 · 373 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +7

Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition

Jean‐Baptiste Telliez, Martin E. Dowty, Lu Wang et al. · ACS Chemical Biology · 2016 · 187 citations · Full text

Jak1 Inhibition, Immunology, Immune Regulation +30

Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors

Robert L. Walsky, Jonathan Bauman, Karine Bourcier et al. · Drug Metabolism and Disposition · 2012 · 149 citations

Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity

Abdul Mutlib, Theunis C. Goosen, Jonathan Bauman et al. · Chemical Research in Toxicology · 2006 · 123 citations

Aldo-keto Reductase, Glycobiology, Udp-glucuronosyltransferases 1A1 +22

Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug

Jonathan Bauman, Kosea S. Frederick, Aarti Sawant et al. · Drug Metabolism and Disposition · 2008 · 83 citations