Lu Wang

PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

Lu Wang, Shuangshuang Li, Huanhua Luo et al. · Journal of Experimental & Clinical Cancer Research · 2022 · 261 citations · Full text

Medicine, Cell Biology, Oncology +17

Critical Role of STAT5 Transcription Factor Tetramerization for Cytokine Responses and Normal Immune Function

Jian‐Xin Lin, Peng Li, Delong Liu et al. · Immunity · 2012 · 201 citations · Full text

Life Sciences, Immunology, Molecular Biology +11

Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition

Jean‐Baptiste Telliez, Martin E. Dowty, Lu Wang et al. · ACS Chemical Biology · 2016 · 196 citations · Full text

Life Sciences, Immunology, Medicinal Chemistry +17

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease

Simon J. Beck, Lan Guo, Aarron Phensy et al. · Nature Communications · 2016 · 174 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Identification of <i>N</i>-{<i>cis</i>-3-[Methyl(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach et al. · Journal of Medicinal Chemistry · 2018 · 171 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14