PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

Lu Wang, Shuangshuang Li, Huanhua Luo, +2

Journal of Experimental & Clinical Cancer Research

Critical Role of STAT5 Transcription Factor Tetramerization for Cytokine Responses and Normal Immune Function

Jian‐Xin Lin, Peng Li, Delong Liu, +10

Immunity

InflammationNormal Immune FunctionTranscriptional RegulationCytokineAutoimmune Disease +11

Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition

Jean‐Baptiste Telliez, Martin E. Dowty, Lu Wang, +33

ACS Chemical Biology

Jak1 InhibitionImmunologyImmune RegulationInnate ImmunityInflammatory Arthritis +28

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease

Simon J. Beck, Lan Guo, Aarron Phensy, +8

Nature Communications

Identification of <i>N</i>-{<i>cis</i>-3-[Methyl(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach, +32

Journal of Medicinal Chemistry

ImmunodeficienciesJanus KinasesImmunologyPharmacotherapyImmunotherapy +20

Hsa_circ_0001666 suppresses the progression of colorectal cancer through the miR‐576‐5p/PCDH10 axis

Jiahui Zhou, Lu Wang, Qingyang Sun, +10

Clinical and Translational Medicine

Exploration of Serum Exosomal LncRNA TBILA and AGAP2-AS1 as Promising Biomarkers for Diagnosis of Non-Small Cell Lung Cancer

Tao Yao, Yuting Tang, Zailin Yang, +9

International Journal of Biological Sciences

PathologyTumor BiologyOncologyCancer DetectionMolecular Diagnostics +15

Deficiency of Interferon-Gamma or Its Receptor Promotes Colorectal Cancer Development

Lu Wang, Yan Wang, Zhiyu Song, +2

Journal of Interferon & Cytokine Research

Cancer ResearchOncologyGastrointestinal OncologyOncogenic AgentMedicine +13

Multi-institutional analysis of radiation modality use and postoperative outcomes of neoadjuvant chemoradiation for esophageal cancer

Steven H. Lin, Kenneth W. Merrell, Jincheng Shen, +15

Radiotherapy and Oncology

Radiation Modality UseEsophageal CancerRadiation TherapyGastrointestinal OncologyMedicine +5

CD4+ T-Cell Modulation of Visceral Nociception in Mice

Monica Verma–Gandhu, Přemysl Berčík, Yasuaki Motomura, +6

Gastroenterology

InflammationPain MedicineT-regulatory CellImmunologyMolecular Pain +7