Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

William Henry Hudson, Julia Gensheimer, Masao Hashimoto, +10

Immunity

InflammationAutoimmune DiseaseAdaptive Immune SystemTransitory T CellsT-regulatory Cell +9

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

Thi‐Sau Migone, Jian‐Xin Lin, Anna Cereseto, +4

Science

InflammationSystems BiologySignal TransductionAutoimmune DiseaseIl-2-independent Growth +13

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

Wei Liao, Jian‐Xin Lin, Lu Wang, +2

Nature Immunology

InflammationCytokineAutoimmune DiseaseLymphocyte DevelopmentCytokine Receptors +9

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

Masao Hashimoto, Koichi Araki, Maria A. Cardenas, +28

Nature

Autoimmune DiseaseT-regulatory CellImmunologyImmune RegulationPd-1 Combination Therapy +6

Interleukin-6 Induction by Tumor Necrosis Factor and Interleukin-1 in Human Fibroblasts Involves Activation of a Nuclear Factor Binding to a κΒ-Like Sequence

Yihong Zhang, Jian‐Xin Lin, J Vilček

Molecular and Cellular Biology

Immune RegulationImmunologyCell DeathPathologyImmunologic Mechanism +19

Regulation of Cell-Type-Specific Interleukin-2 Receptor α-Chain Gene Expression: Potential Role of Physical Interactions between Elf-1, HMG-I(Y), and NF-κ B Family Proteins

Susan John, Raymond Reeves, Jian‐Xin Lin, +4

Molecular and Cellular Biology

Immune RegulationImmunologyImmunologic MechanismImmune SystemIl-2r Alpha +19

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

Aaron M. Ring, Jian‐Xin Lin, Dan Feng, +10

Nature Immunology

InflammationCytokineAutoimmune DiseaseAllergyMedicine +10

Cloning of Human Stat5B

Jian‐Xin Lin, Judy A. Mietz, William S. Modi, +2

Journal of Biological Chemistry

Critical Role of STAT5 Transcription Factor Tetramerization for Cytokine Responses and Normal Immune Function

Jian‐Xin Lin, Peng Li, Delong Liu, +10

Immunity

InflammationNormal Immune FunctionTranscriptional RegulationCytokineAutoimmune Disease +11

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

Vivien Béziat, Juan Li, Jian‐Xin Lin, +57

Science Immunology