Nilantha Sirisoma - Concepedia

Concepedia

Author

Nilantha Sirisoma

University of California, Berkeley

Also Known As

N. S. SIRISOMA, N. S. Sirisoma, N. Sirisoma, Nilantha S. Sirisoma, Nilantha Sirisoma, Sirisoma, N.S.

32

Publications

2.2K

Citations

20

H-Index

42

Concepts

All Affiliations

University of California, Berkeley Wayne State University Myriad Genetics Johns Hopkins University Epic Sciences (United States)

NS

About

Nilantha Sirisoma is an author at University of California, Berkeley specializing in pharmacology, medicine, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	17	1.6K
2	Natural Sciences	14	14	1.4K
3	Biochemistry	14	14	1.4K
4	Biomolecular Engineering	4	4	750
5	Engineering	3	3	76

Nilantha Sirisoma

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24

Publications

2.2K

Citations

20

H-Index

	Year	Citations
The natural polyamine spermine functions directly as a free radical scavenger Hyo Chol Ha, Nilantha Sirisoma, Periannan Kuppusamy, Proceedings of the National Academy of Sciences SpermatogenesisBiochemistryMedicineNatural SciencesPolyamine Spermine	1998	674
α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification Karin M. Höld, Nilantha Sirisoma, Tomoko Ikeda, Proceedings of the National Academy of Sciences	2000	351
A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid Shailaja Kasibhatla, Katayoun A. Jessen, Sergei Maliartchouk, Proceedings of the National Academy of Sciences Chemoprevention StrategyApoptosisImmunologyCell DeathPharmacotherapy	2005	211
MPC-6827: A Small-Molecule Inhibitor of Microtubule Formation That Is Not a Substrate for Multidrug Resistance Pumps Shailaja Kasibhatla, Vijay Baichwal, Sui Xiong Cai, Cancer Research Chemoprevention StrategyCell-based Screening AssayCytoskeletonPharmaceutical ChemistryTumor Biology	2007	123
Discovery of <i>N</i>-(4-Methoxyphenyl)-<i>N</i>,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration Nilantha Sirisoma, Azra Pervin, Hong Zhang, Journal of Medicinal Chemistry Cell DeathPharmacotherapyPharmaceutical ChemistryMedicinal ChemistryEfficacious Anticancer Agent	2009	121
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure–activity relationships of the 1- and 3-positions William Kemnitzer, Jared Kuemmerle, Songchun Jiang, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicineNatural SciencesApoptosisCaspase-based High-throughput	2008	82
Detoxification of α- and β-Thujones (the Active Ingredients of Absinthe): Site Specificity and Species Differences in Cytochrome P450 Oxidation in Vitro and in Vivo Karin M. Höld, Nilantha Sirisoma, John E. Casida Chemical Research in Toxicology	2001	79
Discovery of 2-Chloro-<i>N</i>-(4-methoxyphenyl)-<i>N</i>-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity Nilantha Sirisoma, Shailaja Kasibhatla, Azra Pervin, Journal of Medicinal Chemistry ApoptosisCell DeathPharmacotherapyCell Death MechanismsPharmaceutical Chemistry	2008	65
Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring Nilantha Sirisoma, Azra Pervin, Hong Zhang, Bioorganic & Medicinal Chemistry Letters Structure–activity RelationshipMolecular PharmacologyMedicinal ChemistryBiochemistryMedicine	2010	49
Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group Nilantha Sirisoma, Shailaja Kasibhatla, Bao Nguyen, Bioorganic & Medicinal Chemistry Molecular PharmacologyBiochemistryMedicineNatural SciencesApoptosis	2006	42

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