Pieter B. Burger

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

Sharon A. Swanger, Wenjuan Chen, Gordon Wells et al. · The American Journal of Human Genetics · 2016 · 178 citations · Full text

Signal Transduction, Rare Variants, Functional Selectivity +10

Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators

Timothy M. Acker, Hongjie Yuan, Kasper B. Hansen et al. · Molecular Pharmacology · 2011 · 102 citations · Full text

Structural Determinants of d-Cycloserine Efficacy at the NR1/NR2C NMDA Receptors

Shashank M. Dravid, Pieter B. Burger, Anand Prakash et al. · Journal of Neuroscience · 2010 · 100 citations · Full text

Molecular Biology, Pharmacotherapy, Chemical Biology +16

Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy

Wenjuan Chen, Anel Tankovic, Pieter B. Burger et al. · Molecular Pharmacology · 2017 · 78 citations · Full text

Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator

Alpa Khatri, Pieter B. Burger, Sharon A. Swanger et al. · Molecular Pharmacology · 2014 · 76 citations · Full text