Timothy M. Acker

Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases

Chun-Jun Guo, Fangyuan Chang, Thomas P. Wyche et al. · Cell · 2017 · 213 citations · Full text

Protease Inhibitors, Probiotic, Microbiology +5

Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators

Timothy M. Acker, Hongjie Yuan, Kasper B. Hansen et al. · Molecular Pharmacology · 2011 · 102 citations · Full text

Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective<i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor Antagonists

Cara A. Mosley, Timothy M. Acker, Kasper B. Hansen et al. · Journal of Medicinal Chemistry · 2010 · 84 citations · Full text

Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs

Nan Bai, Kristin M. Riching, Aman Makaju et al. · Journal of Biological Chemistry · 2022 · 78 citations · Full text

Protein Assembly, Molecular Biology, Target Protein Ubiquitination +20

A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons

Sharon A. Swanger, Katie M. Vance, Timothy M. Acker et al. · ACS Chemical Neuroscience · 2017 · 52 citations · Full text