Role of Calcium Signaling Pathway‐Related Gene Regulatory Networks in Ischemic Stroke Based on Multiple WGCNA and Single‐Cell Analysis

Abstract

Calcium signaling pathway-related genes (<i>AC079305</i>.10, <i>BCL10</i>, <i>BCL2A1</i>, <i>BRE-AS1</i>, <i>DYNLL2</i>, <i>EREG</i>, and <i>PTGS2</i>) and TFs (<i>JUN</i>, <i>IRF9</i>, <i>ETV5</i>, and <i>PPARA</i>) were identified to play a key role in IS. This study provides a new perspective and basis for investigating the pathogenesis of IS and developing new therapeutic approaches.