Concepedia

Differential Expression Analysis

Differential Expression Analysis is a computational method in gene expression analysis that identifies statistically significant variations in gene expression levels between distinct biological conditions or cell populations, distinguishing itself from other genomic data analysis techniques by focusing specifically on expression differences attributable to experimental or biological factors.

7.1K

Publications

1.2M

Citations

29.5K

Authors

4.9K

Institutions

Publications per year

2017–2026

1.9K

Variants

Time Series Expression AnalysisTime-series Expression Analysis

Parents

Children

Publications

7.1K

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

, , +9

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

, , +15

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson, Davis J. McCarthy, Gordon K. Smyth · Bioinformatics · 2009 · 44.5K citations · Full text

, , +14

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research · 2015 · 43K citations · Full text

, , +17

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 20.1K citations · Full text

, , +14

1–5 of 7.1K

Authors

29.5K

  1. GK
    Gordon K. Smyth

    Walter and Eliza Hall Institute of Medical Research, Australia

    46 publications · 131.6K citations

    39

    h-index

  2. MD
    Mark D. Robinson

    University of Zurich, Switzerland

    26 publications · 65.9K citations

    23

    h-index

  3. WH
    Wolfgang Huber

    European Molecular Biology Laboratory, Germany

    24 publications · 128.5K citations

    22

    h-index

  4. RA
    Rafael A. Irizarry

    Johns Hopkins University, United States

    22 publications · 27.5K citations

    22

    h-index

  5. TP
    Terence P. Speed

    Walter and Eliza Hall Institute of Medical Research, Australia

    24 publications · 15.7K citations

    21

    h-index

1–5 of 29.5K

Institutions

4.9K

  1. Harvard University

    Cambridge, United States

    78 h-index

    518 publications

    298.1K citations

  2. Stanford University

    Stanford, United States

    67 h-index

    471 publications

    482.4K citations

  3. National Institutes of Health

    Bethesda, United States

    54 h-index

    353 publications

    84.9K citations

  4. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    52 h-index

    219 publications

    459.7K citations

  5. Johns Hopkins University

    Baltimore, United States

    51 h-index

    367 publications

    122K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    47 h-index

    193 publications

    168.6K citations

  7. University of Washington

    Seattle, United States

    46 h-index

    203 publications

    50.7K citations

  8. University of California, Berkeley

    Berkeley, United States

    44 h-index

    131 publications

    62.7K citations

1–8 of 4.9K

Venues

  1. Bioinformatics

    552 publications · 133.1K citations

    127

    h-index

  2. Nucleic Acids Research

    253 publications · 109.4K citations

    89

    h-index

  3. BMC Bioinformatics

    424 publications · 51.9K citations

    86

    h-index

  4. Genome biology

    104 publications · 174.1K citations

    67

    h-index

  5. BMC Genomics

    194 publications · 13.7K citations

    63

    h-index

1–5