Concepedia

Single-cell Differential Expression

Single-Cell Differential Expression is a computational method in transcriptomics that identifies statistically significant differences in gene expression levels at the resolution of individual cells, distinguished from bulk-level approaches by its ability to detect heterogeneous expression patterns across cell populations.

202

Publications

22.8K

Citations

1.3K

Authors

475

Institutions

Publications per year

2017–2026

162

Parents

Publications

202

Single-cell mRNA quantification and differential analysis with Census

Xiaojie Qiu, Andrew J. Hill, Jonathan S. Packer et al. · Nature Methods · 2017 · 2.1K citations

, , +14

Bayesian approach to single-cell differential expression analysis

Peter V. Kharchenko, Lev Silberstein, David T. Scadden · Nature Methods · 2014 · 1.5K citations · Full text

, , +14

Confronting false discoveries in single-cell differential expression

Jordan W. Squair, Matthieu Gautier, Claudia Kathe et al. · Nature Communications · 2021 · 987 citations · Full text

, , +17

Differential abundance testing on single-cell data using k-nearest neighbor graphs

Emma Dann, Neil C. Henderson, Sarah A. Teichmann et al. · Nature Biotechnology · 2021 · 928 citations · Full text

, , +16

Bias, robustness and scalability in single-cell differential expression analysis

Charlotte Soneson, Mark D. Robinson · Nature Methods · 2018 · 884 citations

, , +12

1–5 of 202

Authors

1.3K

  1. MD
    Mark D. Robinson

    University of Zurich, Switzerland

    8 publications · 1.7K citations

    8

    h-index

  2. CS
    Charlotte Soneson

    SIB Swiss Institute of Bioinformatics, Switzerland

    6 publications · 1.7K citations

    6

    h-index

  3. JC
    John C. Marioni

    European Bioinformatics Institute, United Kingdom

    5 publications · 1.3K citations

    5

    h-index

  4. SD
    Sandrine Dudoit

    University of California, Berkeley, United States

    4 publications · 1.2K citations

    4

    h-index

  5. BV
    Beate Vieth

    Ludwig-Maximilians-Universität München, Germany

    4 publications · 502 citations

    4

    h-index

1–5 of 1.3K

Institutions

475

  1. Harvard University

    Cambridge, United States

    13 h-index

    47 publications

    7.5K citations

  2. University of California, Berkeley

    Berkeley, United States

    12 h-index

    36 publications

    4.1K citations

  3. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    9 h-index

    27 publications

    4.8K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    8 h-index

    14 publications

    1.7K citations

  5. University of Zurich

    Zurich, Switzerland

    8 h-index

    24 publications

    4.4K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    17 publications

    1.1K citations

  7. Broad Institute

    Cambridge, United States

    7 h-index

    22 publications

    714 citations

  8. California Institute of Technology

    Pasadena, United States

    7 h-index

    19 publications

    645 citations

1–8 of 475

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 28 publications · 857 citations

    17

    h-index

  2. Bioinformatics

    14 publications · 1.8K citations

    13

    h-index

  3. Nature Communications

    12 publications · 3.1K citations

    12

    h-index

  4. Genome biology

    10 publications · 1.2K citations

    10

    h-index

  5. Nature Methods

    7 publications · 5.2K citations

    7

    h-index

1–5