Concepedia

Single-cell mRNA quantification and differential analysis with Census

Xiaojie Qiu, Andrew J. Hill, Jonathan S. Packer, Dejun Lin, Yi-An Ma, Cole Trapnell

Nature Methods · 2017 · 2.1K citations · 46 references

Concepts

Life SciencesCell BiologyMolecular BiologyGene ExpressionSingle-cell BioinformaticsTranscriptomicsCell ClusteringCell-type-specific TranscriptomicsSingle-cell AnalysisSingle-cell GenomicsSingle-cell Rna Sequencing AnalysisSingle-cell TranscriptomicsNormalization Of Single-cell DataSingle-cell Differential ExpressionSingle-cell Differential Expression AnalysisSingle-cell Gene Expression ProfilingSingle-cell Rna Sequencing

References

46

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson, Davis J. McCarthy, Gordon K. Smyth · Bioinformatics · 2009 · 44.5K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +14

Differential expression analysis for sequence count data

Simon Anders, Wolfgang Huber · Genome biology · 2010 · 16.4K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

Near-optimal probabilistic RNA-seq quantification

Nicolas Bray, Harold Pimentel, Páll Melsted et al. · Nature Biotechnology · 2016 · 11K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +6

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby et al. · Nature Biotechnology · 2014 · 7.8K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16