Concepedia

Single-cell Differential Expression Analysis

Single-Cell Differential Expression Analysis is a computational method in genomics that identifies statistically significant differences in gene expression levels across individual cells, enabling the discovery of cell-type-specific transcriptional dynamics within heterogeneous biological populations.

139

Publications

17.4K

Citations

757

Authors

315

Institutions

Publications per year

2017–2026

114

Parents

Publications

139

Single-cell mRNA quantification and differential analysis with Census

Xiaojie Qiu, Andrew J. Hill, Jonathan S. Packer et al. · Nature Methods · 2017 · 2.1K citations

, , +14

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

Atray Dixit, Oren Parnas, Biyu Li et al. · Cell · 2016 · 1.9K citations · Full text

, , +14

Bayesian approach to single-cell differential expression analysis

Peter V. Kharchenko, Lev Silberstein, David T. Scadden · Nature Methods · 2014 · 1.5K citations · Full text

, , +14

Confronting false discoveries in single-cell differential expression

Jordan W. Squair, Matthieu Gautier, Claudia Kathe et al. · Nature Communications · 2021 · 987 citations · Full text

, , +17

Differential abundance testing on single-cell data using k-nearest neighbor graphs

Emma Dann, Neil C. Henderson, Sarah A. Teichmann et al. · Nature Biotechnology · 2021 · 928 citations · Full text

, , +16

1–5 of 139

Authors

757

  1. JC
    John C. Marioni

    European Bioinformatics Institute, United Kingdom

    5 publications · 1.3K citations

    5

    h-index

  2. MD
    Mark D. Robinson

    University of Zurich, Switzerland

    5 publications · 1.3K citations

    5

    h-index

  3. CZ
    Christoph Ziegenhain

    Ludwig-Maximilians-Universität München, Germany

    4 publications · 502 citations

    4

    h-index

  4. SP
    Swati Parekh

    Ludwig-Maximilians-Universität München, Germany

    4 publications · 502 citations

    4

    h-index

  5. WE
    Wolfgang Enard

    Ludwig-Maximilians-Universität München, Germany

    4 publications · 502 citations

    4

    h-index

1–5 of 757

Institutions

315

  1. Harvard University

    Cambridge, United States

    11 h-index

    33 publications

    10.1K citations

  2. University of California, Berkeley

    Berkeley, United States

    9 h-index

    28 publications

    3.7K citations

  3. California Institute of Technology

    Pasadena, United States

    7 h-index

    20 publications

    679 citations

  4. Wellcome Sanger Institute

    Cambridge, United Kingdom

    6 h-index

    10 publications

    3.4K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    10 publications

    1.6K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    31 publications

    4.9K citations

  7. University of Zurich

    Zurich, Switzerland

    5 h-index

    15 publications

    3.2K citations

  8. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    5 h-index

    15 publications

    3.2K citations

1–8 of 315

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 25 publications · 645 citations

    16

    h-index

  2. Genome biology

    11 publications · 1.1K citations

    11

    h-index

  3. Bioinformatics

    9 publications · 836 citations

    9

    h-index

  4. Nature Communications

    8 publications · 2.7K citations

    8

    h-index

  5. Nature Methods

    6 publications · 4.8K citations

    6

    h-index

1–5