Concepedia

FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma

Giulia Cristinziano, Manuela Porru, Dante Lamberti, Simonetta Buglioni, Francesca Rollo, Carla Azzurra Amoreo, Isabella Manni, Diana Giannarelli, Cristina Cristofoletti, Giandomenico Russo,

Journal of Hepatology · 2021 · 82 citations · 28 references

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28

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Laura Broutier, Gianmarco Mastrogiovanni, Monique M.A. Verstegen et al. · Nature Medicine · 2017 · 1.5K citations · Full text

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The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

Michelangelo Cordenonsi, Francesca Zanconato, Luca Azzolin et al. · Cell · 2011 · 1.4K citations · Full text

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Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

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Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

Laura Broutier, Amanda Andersson-Rolf, Christopher J. Hindley et al. · Nature Protocols · 2016 · 879 citations · Full text

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Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Yi-Mi Wu, Fengyun Su, Shanker Kalyana‐Sundaram et al. · Cancer Discovery · 2013 · 738 citations · Full text

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